Thursday, August 27, 2020

Canons of Taxation

A decent duty framework is one which is structured based on a suitable arrangement of standards (rules). The duty framework should find some kind of harmony between the enthusiasm of the citizen and that of expense specialists. Adam Smith was the principal financial specialist to build up a rundown of Canons of Taxation. These standards are still viewed as qualities or highlights of a decent assessment framework. Adam Smith gave following four significant groups of tax collection. 1. Standard of Equity The rule targets giving financial and social equity to the individuals. As indicated by this rule, each individual should pay to the legislature relying on his capacity to pay. The rich class individuals should pay higher charges to the legislature, on the grounds that without the assurance of the administration specialists (Police, Defense, and so forth ) they couldn't have earned and made the most of their salary. Adam Smith contended that the expenses ought to be corresponding to pay, I. e. , residents should pay the assessments in relation to the income which they separately appreciate under the insurance of the state. 2. Standard of Certainty As per Adam Smith, the duty which an individual needs to pay ought to be sure, not subjective. The citizen should know ahead of time how much assessment he needs to pay, at what time he needs to settle the duty, and in what structure the expense is to be paid to the legislature. At the end of the day, each duty ought to fulfill the standard of conviction. Simultaneously a decent assessment framework additionally guarantees that the administration is likewise sure about the sum that will be gathered by method of expense. 3. Group of Convenience The mode and timing of assessment installment ought to be beyond what many would consider possible, helpful to the citizens. For instance, land income is gathered at time of reap personal duty is deducted at source. Helpful duty framework will urge individuals to cover charge and will expand charge income. 4. Standard of Economy This rule expresses that there ought to be economy in charge organization. The expense of assessment assortment ought to be lower than the measure of duty gathered. It may not fill any need, if the charges forced are broad however are hard to manage. In this way, it would look bad to force certain assessments, in the event that it is hard to oversee. Extra Canons of Taxation v Activities and elements of the administration have expanded fundamentally since Adam Smiths time. Government are relied upon to keep up monetary strength, full business, lessen pay disparity amp; advance development and improvement. Expense framework ought to be to such an extent that it meets the prerequisites of developing state exercises. As needs be, present day financial specialists gave following extra groups of tax collection. 5. Ordinance of Productivity It is otherwise called the standard of financial ampleness. As indicated by this guideline, the duty framework ought to have the option to yield enough income for the treasury and the administration ought to have no compelling reason to fall back on shortage financing. This is a decent guideline to follow in a creating economy. 6. Group of Elasticity According to this ordinance, each assessment forced by the administration ought to be flexible in nature. At the end of the day, the salary from duty ought to be equipped for expanding or diminishing as indicated by the necessity of the nation. For instance, if the administration needs more pay at time of emergency, the expense ought to be fit for yielding more salary through increment in its rate. . Ordinance of Flexibility It should be effectively feasible for the specialists to reconsider the duty structure both as for its inclusion and rates, to suit the changing prerequisites of the economy. With changing time and conditions the duty framework should be changed absent a lot of trouble. The d uty framework must be adaptable and not unbending. 8. Standard of Simplicity The duty framework ought not be muddled. That makes it hard to comprehend and regulate and brings about issues of understanding and debates. In India, the endeavors of the legislature as of late have been to make the framework basic. 9. Ordinance of Diversity This rule expresses that the legislature should gather charges from various sources instead of focusing on a solitary wellspring of duty. It isn't fitting for the legislature to rely on a solitary wellspring of assessment, it might bring about disparity to the specific area of the general public; vulnerability for the administration to raise reserves. In the event that the duty income originates from expanded source, at that point any decrease in charge income by virtue of any one reason will undoubtedly be little.

Saturday, August 22, 2020

Modern-day Witch Hunts :: essays research papers

Is the informer in every case sacred at this point? Is it safe to say that they were brought into the world toward the beginning of today as spotless as God's fingers? I'll mention to you what's strolling Salem-retaliation is strolling Salem. We are what we generally were in Salem, yet now the little insane youngsters are clanking the keys of the realm, and regular retribution composes the law! (p73, The Crucible) Arthur Miller's exemplary play, The Crucible, is about the witch-chases and preliminaries in seventeenth century Salem, Massachusetts. What begins with a few young ladies rehearsing European white enchantment in the forested areas raises to an enormous delirium, with the "afflicted" young ladies dishonestly blaming even the regarded ladies in the network of being witches. Anxious to "utterly squash the workers of the devil", church pioneers and townspeople demand attempting the blamed. The discipline for neglecting to admit to black magic is passing by hanging. At long last, many are hanged for nonexistent wrongdoings, for which no genuine confirmation is ever introduced, the main proof being the expression of a bunch of young ladies. Mill operator composed The Crucible as a corresponding to the anticommunist madness in the 1940's. It might likewise be viewed as a mirror to Hitler's Germany, and the pseudo-study of the time which directed "purity". Today, in any case, The Crucible demonstrates a similarity to a completely unique sort of social madness. Allegations of sexual-maltreatment against kid care suppliers and others are presently in some cases alluded to as "witch hunts" when the informers are associated with lying, as in Miller's play. Youngsters' promoters will obviously reveal to us that we should accept kids' cases of misuse, in light of the fact that, appallingly, it occurs. Nonetheless, an ongoing pattern has indicated that an ever increasing number of allegations are bogus, and in any event, when the blamed are discovered guiltless, their lives can be changed until the end of time. This paper will inspect the similitudes between Miller's The Crucible, and the sexu al-misuse "witch hunts" of today. Gordon Waugh, individual from Casualties Of Sexual Allegations (COSA) composes: †¦many individuals currently gain "victimhood" through guiding. Being a "victim" draws compassion. It clarifies the disasters, the disappointments, the hardships, the medical issues and the failure of life. It soothes individuals of a portion of life's regular weights: managing unpredictability, confronting things outside their ability to control, and tolerating obligation regarding choices and activities. Numerous instructors credit their customers' troubles to since quite a while ago covered "repressed" recollections of youth sexual maltreatment. They help customers to open these, and change their pasts. Customers cut off every previous tie with "families of origin" and encircle themselves just with other "survivors", to forestall affirmation or disavowal.

Friday, August 21, 2020

Writing an Effective APA Research Paper

Writing an Effective APA Research PaperAn efficient way to write a good APA research paper is to get hold of an APA research paper sample. While this may seem like an ideal situation, a lot of people fail to do so as they simply do not know what they are looking for in this document.A research paper sample is used by a lot of schools and universities to help them make sure that the paper that they write has substance. The reason why they use them is because many times they do not understand the fundamental concepts behind the various theories and terms that they study. It also helps them to be able to test the students' ability to understand the topics covered in the paper and make sure that they have the required skills to write one.Basically, an APA research paper sample will contain various strategies and insights that can help you be able to come up with a better idea for your paper. One of the best strategies is the APA brainstorming technique which allows you to come up with id eas on your own without having to explain it. Once you have figured out a concept or a generalization, you can come up with more detailed descriptions about it to fit the boundaries of the paper.There are also other strategies that are usually included in an APA research paper sample. One of these is brainstorming, which enables you to come up with original ideas and concepts for the specific topic of the paper. As you probably know, most students tend to use existing concepts as a basis for their ideas rather than coming up with original concepts. By using an APA research paper sample, you will be able to come up with more original ideas and you will be able to save time.You should also consider whether or not you need to read the entire APA research paper sample in order to work on the paper. If you think that you don't need to read it, then just skip it. However, if you really want to be able to read the entire document, you should spend some time going through it. This will allo w you to understand how it works and what it actually contains.Another important part of the APA research paper sample is the structure. Since the samples are generally of a single chapter, it will help you to have a clear understanding of how the chapters are related to each other. This way, you will be able to come up with a structure for your paper that is related to the information you want to cover.Another part of the APA research paper sample is the sections of the paper. This includes the introduction, the body, the conclusion, and the methods section. By reading through these sections, you will be able to come up with a clearer idea on how to structure your paper and what type of topics you should cover in it.One thing that you should always remember when you are looking for an APA research paper sample is that these are only examples. They will never tell you the exact format of your paper. The best thing that you can do is to work on it yourself in order to come up with th e best structure that fits your paper the best.

Monday, May 25, 2020

HRs Impact on Long Term Environmental Sustainability - Free Essay Example

Sample details Pages: 8 Words: 2499 Downloads: 7 Date added: 2017/06/26 Category Management Essay Type Essay any type Level High school Did you like this example? Introduction This essay focuses on the role of human resources (HR) in achieving environmental sustainability. It starts by very briefly explaining what environmental sustainability is, and why it is so important for individuals and organisations to contribute to achieving goals and targets related to sustainability. It next briefly explains what is meant by HR. Don’t waste time! Our writers will create an original "HRs Impact on Long Term Environmental Sustainability" essay for you Create order Next it considers the ways in which HR managers are likely to be involved in supporting their organisations to reach sustainability targets. A focus on one organisation then allows some ideas to be developed that can form the basis of recommendations for improvement of environmental sustainability key to HR. Environmental sustainability is a component of the sustainable development concept. This concept is described as development à ¢Ã¢â€š ¬Ã…“that meets the needs of the present without compromising the ability of future generations to meet their own needs (World Commission on Environment and Development, 1987:43). Essentially, it argues that to sustain life both human and animal the provision of clean water and air, and energy obtained from renewable resources are vital (Sutton, 2004). Human Resource departments might not seem the natural home of a focus on environmental sustainability, as often the burden of responsibility in an organisation is placed on an operations ma nager. However, there is definitely a role to play for human resources. In researching this issue, care must be taken to include terms that encompass the HR function these can include Human Resource Management (HRM), Employment Services (ES), Human Capital, Personnel and others (Abusafia, 2012). HR Management Support for the Drive Towards Environmental Sustainability There is a range of HR activities that directly contribute to the environmental sustainability of an organisation. These often revolve around the development of green jobs and the infrastructure, training, personal development planning, performance management, communication, attitude monitoring and other aspects that go along with the creation of new posts, or new components of existing posts (Jackson, 2012). Liebowitz (2010) argues that the role of HR is more fundamental and deep seated than developing processes he suggests that the HR department has a very significant role to play in the creation of a companys sustainability culture, as it is professionally trained to change the attitudes and behaviours of employees, from senior executives to the most junior of staff (Liebowitz, 2010). Liebowitz also argues that HR managers are far removed from the old traditional personnel manager. Today, HR staff are likely to know much more about the business, and they use a human capital ma nagement approach to underpin the development of staff to achieve environmental objectives (Lebowitz, 2010). Wilkins (2014) identifies the skill to motivate and encourage employees to become engaged with sustainability programmes within an organisation as key to their success (Wilkins, 2014). In fact, Wilkins argues that to achieve success, three key components are necessary communication, education and motivation. Communication includes good environmental practice for employees (reducing energy use), and highlighting individual and organisational environmental achievements (Wilkins, 2014). Education can be used to provide employees with practical information about integrating environmental objectives into their daily work, for example, engaging in recycling activities; this can also improve productivity as all staff are working towards a common purpose (Wilkins, 2014). Motivation in the form of an environmentally focussed rewards programme can ensure that employees remain committe d, and can actually help retention of valuable staff (Wilkins, 2014). Cohen et al (2012) suggest that one influencing factor on the role HR plays in supporting environmental sustainability, will be the motivations behind the organisations move towards more sustainable operations and strategies. They argue that the route taken may make the HR contribution easier or more difficult. They identify a values-based route, a strategic route and a defensive route. The first is associated mostly with the personal principles of the founders of small businesses some of which may have become much larger (Cohen et al, 2012). The second is those businesses that identify opportunities in redesigning products or services to expand into markets where environmental characteristics are valued (Cohen et al, 2012). Lastly, the defensive route occurs when companies come under pressure to change their approach, perhaps because of a pollution incident (Cohen et al, 2012). It is clear that each of these routes will have a different impact on the work of the HR manager: where the business chooses to commit to environmental objectives, there is likely to be a positive culture, whilst companies forced into accepting change in environmental attitudes are likely to generate at least some resistance (Harmon et al, 2010). What the above discussion shows is that there is motivation for HR managers and departments to become involved in supporting a move towards environmental sustainability in their organisation. There are a number of HR tools that can be used to embed such sustainability objectives into an organisation. There are four main areas where such tools may be deployed: employee attraction and selection; employee training, development and compensation; creating a sustainable organisational climate; and, management support and communication (Cohen et al, 2012). Having a good environmental profile has been found to attract high quality employees (Government of Canada, n.d.), and t o retain these employees for longer than average retention periods (Ernst Young, 2013), and the HR department can therefore use a commitment to environmental sustainability in their job advertising, ensuring that they have an edge over their competitors (Ernst Young, 2013). To maintain and energise staff to commit to environmental processes, i.e. to motivate employees (Human Resource Excellence, 2012) it is necessary to provide targeted training, for example, in life cycle analysis to reduce inefficiency and waste, and to include formal evaluations of such commitment i.e. targets to be achieved in job plans (Manufacturing Skills Australia, 2015). Changing an organisations culture is often the most challenging, but also the most necessary approach. While there may be commitment at the senior management level, this is likely to decline the further down the organisational hierarchy you go (Petrini and Pozzebon, 2010). This is especially true in traditional industries, such as constru ction, where male dominated heavy labour has little cultural awareness of environmental issues (Built Environment Sustainability Training, 2014). Management support through communication that relates to employees lives can indicate an overall organisational commitment to environmental sustainability, and can encourage people to integrate environmental principles throughout their daily lives (Fleischer, 2009). HR can assist in all of these areas through training, communication, incentivisation, PDP and other such tools. The following section provides some recommendations for such actions in one organisation. Recommendations for Improving Environmental Sustainability Through HR The organisation chosen for the case study is a construction company, McGregor Construction, which is located in the Scottish Highlands. This company was formed in 1977, but has previous history going back 132 years (McGregor Construction n.d.). Annual turnover is around  £9.5 million, and the company covers the construction spectrum, including building projects for hospitals, sports stadiums, shopping centres, council housing, and private housing (McGregor Construction, n.d.). Work includes both new build and repairs to existing properties, some of these being very old and architecturally important. It has 68 employees, many of whom have been with the company for a long time (Endole, 2015). . The employee profile is important in that it is largely male (80%), and largely older age groups, with 63% in the 40 56 years age bracket, and 7% in the 57 70, 5% in the 70+, while 15% is in the 25 39 years and 10% in the 18 24 bracket. Many of the older employees are highly ski lled, not only in modern building techniques but in traditional craft based skills building techniques. The company has come under increasing pressure to develop a strategic and operational approach to environmental management. This pressure has arisen partly from the industry itself, as the construction sector has made substantial efforts to integrate sustainability objectives into the activities and functions of the industry (European Commission, 2012). It has also arisen from pressure through the supply chain as McGregor is a supplier of services to a number of large customers, who have a commitment to greening their supply chains. Finally, the company is aware that they are not as efficient as they could be in managing their energy use and waste, and are seeking to improve these aspects to save money. The five main environmental objectives the company has identified are: to reduce waste throughout the company by 40% in the next year, to reduce fuel use and on site energy use d combined by 40% in the next year, to increase the use of recycled materials by 10%, and to support community environmental objectives, and to reduce on site noise pollution, again all in the next financial year. There are a number of recommendations that can be made to support the HR manager who is assisted by one member of staff for administrative purposes in achieving these objectives. Using the four main areas of HR related improvement identified by Cohen et al (2012), a range of specific actions may be taken. First, employee attraction and selection. One HR tool is to integrate the selection of new employees with the long term environmental strategy of the company so for all future employees it is recommended that an environmental component is built into job plans or descriptions. Specifically, waste management and energy use reduction should be a target tasked for all new employees. This should be followed up by the inclusion of environmental stewardship questions as part of the interview process; candidates could even be asked to give a very short presentation on the importance of environmental management in the construction industry. By using these tools, it not only signals to prospective employees that the company is seriously committed to environmental improvement, and that if they are employed they will be expected to contribute. It may also attract individuals who might otherwise have ignored a small company in favour of finding a large one with an established sustainability strategy. Second, employee training, development and compensation. Here HR can have a substantial input. Environmental training programmes can be devised and be mandatory for all staff (CIPD, 2015), with specific focus for some staff on certain issues. For example, for people labouring or working actually in building processes, a focus on the handling of materials and reduction of waste would be a sensible inclusion. Training for all staff on energy conservation i .e. switching off machinery, lights and so on when not required, would be an easy initial approach. Training programmes should be aligned with the companys environmental objectives, so that the training can directly feed into the achievement of the objectives. Compensation is a useful approach, and can be operationalised by HR in a number of ways. For example, Intel uses an Environmental Excellence award programme, which incentivises environmental behaviour through peer review of nominations for environmental innovation (Patton, 2013). One outcome was the reduction of energy consumption of chillers, boiler plants and vacuum pumps that in just one factory is estimated to save $38 million (Patton, 2013). On a much smaller scale, such a programme could be supported and instigated in McGregors with innovations in material recycling, energy use reduction, fuel saving, building technologies and techniques and carbon reduction as expected outcomes. Third is the creation of a sustainabl e organisational climate. Here HR can contribute by using sustainability oriented entry, performance and exit practices (Verburg and Den Hartog, 2006), as long as senior management recognises the importance of integrating HR into the overall company sustainability strategy (Putter, 2010). In achieving a sustainability oriented climate, HR can be especially useful in supporting the work of line managers in recruiting more employees, managing their environmental performance, and ensuring that when they leave they do so with substantial environmental awareness, and respect for what the company have done. Indeed, if HR integrates environmental issues across the whole company through workforce planning then this directly feeds into the organisational climate (Petrini and Pozzebon, 2010) The final area of recommendations is for management support and communication. It is vital that the company directors and senior managers demonstrate absolute commitment to environmental sustainability and they should lead by example. An employee of the month scheme could be instituted with public recognition of an individuals environmental achievements being a well recognised effective approach (Silverman, 2004). Employees seeing that senior managers are rewarding such behaviours are likely to engage with further activities when they are introduced by HR through the tools previously described. Conclusions It is clear the HR has a substantial role to play in the integration of environmental sustainability in any organisation and has an increasing range of tools and systems that can be used to achieve this. References Abusafia, A. (2012). Rebranding of the Human Resources Department. Available at: https://hr-management.hr.toolbox.com/groups/strategy-administration/management-staff/rebranding-of-the-human-resources-department-4671333 Built Environment Sustainability Training. (2014).Summary Skills Needs Analysis for Waste in Construction. Cardiff: Built Environment Sustainability Training. CIPD. (2015). Environmental and Sustainability Policy. Available at: https://www.cipd.co.uk/cipd-hr-profession/about-us/environmental-sustainability-policy.aspx Cohen, E., Taylor, S., and Muller-Camen, M. (2012). HRMs Role in Corporate Social and Environmental Responsibility. Alexandria VA: SHRM Foundation. Endole. (2015). McGregor Construction (Highlands) Limited. Available at: https://www.endole.co.uk/company/SC061518/mcgregor-construction-highlands-limited Ernst Young. (2013). Role of HR in Driving Sustainable Business Practices. Kolkata India: Ernst Young. European Commission. (2012). CO MMUNICATION FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT AND THE COUNCIL Strategy for the sustainable competitiveness of the construction sector and its enterprises /* COM/2012/0433 final. Brussels: European Commission. Fleischer, D. (2009). Three Tips for Engaging Employees in Sustainability. Available at: https://www.triplepundit.com/2009/09/employee-engagement-three-tips-for-engaging-employees-in-sustainability/ Government of Canada. (n.d.). SME Sustainability Roadmap. Available at: https://www.ic.gc.ca/eic/site/csr-rse.nsf/eng/rs00591.html Harmon, J., Fairfield, K. D., and Wirtenberg, J. (2010). Missing an Opportunity: HR Leadership in Sustainability. People and Strategy, 33(1), pp. 16-21. Human Resource Excellence. (n.d.). Importance of Human Resource Management. Available at: https://www.humanresourceexcellence.com/importance-of-human-resource-management/ Jackson, S.E. (2012). The Role of Human Resource Management in Achieving Environmental Sustainability. In: S.E. Jackson,. D.S. Ones., and S. Dlichert. (eds.) (2012). Managing Human Resources for Environmental Sustainability. San Francisco CA: Jossey Bass. Liebowitz, J. (2010). The Role of HR in Achieving a Sustainability Culture. Journal of Sustainable Development, 3 (4), pp. 50 57. Manufacturing Skills Australia. (2015). Planning and Procedures. Available at: https://sustainabilityskills.net.au/what-is-sustainability/sustainability-practice/strategy-and-management/planning-and-procedures/ McGregor Construction. (n.d.) The Company. Available at: https://www.mcgregors.net/index.php Patton, C. (2013). Rewarding Best Behaviours. Human Resource Executive [online] 09 December. Available at: https://www.hreonline.com/HRE/view/story.jhtml?id=534356443 Petrini, M., and Pozzebon, M. (2010). Integrating Sustainability Into Business Practices: Learning from Brazilian Firms. Brazilian Administration Review, 7 (4), pp. 362 378. Putter, L. (2010). Organizational Climate and Perfor mance. Delft: Delft University of Technology. Silverman, D. (2004). Non-Financial Recognition: The Most Effective of Rewards? Brighton: Institute for Employment Studies. Sutton, P. (2004). A Perspective on Environmental Sustainability? Fairfield, Victoria: Green Innovations. Verburg, R.M., and Den Hartog, D.N. (2006). Human Resource Management for Advanced Technology. In R.M. Verburg., R.J. Ortt., and W.M. Dicke,W.M. (Eds.) (2006). Managing Technology and Innovation: An Introduction. London: Routledge. Wilkins, S. (2014). How HR Can Drive Sustainability. HR [online] 30 April. Available at: https://www.hrmagazine.co.uk/article-details/how-hr-can-drive-sustainability World Commission on Environment and Development. (1987). Our Common Future. Oxford University Press: Oxford.

Friday, May 15, 2020

African Americans And The Criminal Justice System

Introduction African American males are overrepresented in the criminal justice and many times are subject to harsher sentences than their Caucasian counterparts. African American males also experience racial profiling and have more negative interactions than any other population in the United States. Ibie, Obie, and Obiyan states, â€Å"African Americans have continued to be the repository for American crime and to be treated as amalgamation of presumed group trait rather than as individuals†. This topic is important because African American adolescents are less likely to be referred to rehabilitation or diversion programs and more likely to be sent to juvenile and/or prison. History has not been kind to African Americans and the injustices experienced by African Americans in the criminal justice system is extremely high. According to Weatherspoon, â€Å"The Supreme Court condoned and perpetuated many of the present day stereotypical biases concerning African Americans in the landma rk decision of Dred Scott v. Sanford†. Over that past few years, with the advent of social media, the world is becoming more aware of the injustices and brutality suffered by African American males in the justice system. Many view this as a new phenomenon, but others know this abuse has always occurred, it is just now there are cameras taping the violence. Many people are waking up to what is occurring, but there are many others who are denial and who refuse to acknowledge the oppression and racismShow MoreRelatedAfrican Americans And The Criminal Justice System Essay1688 Words   |  7 PagesThere are many ways the criminal justice system plays a huge role in the discrimination against all people of color. 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The dominant socialization indifference is theoretically associated with Marxist Criminology schools of thought, in particular conflict theory. Qualitative, empirical, and historical data supports Marxist criminology based on capitalism, conflict, and the disparity treatment of the Afro-American male within the criminal justice system: police, courtsRead MoreThe Criminal Justice System : An Analysis Of Income And Racial Inequality Essay1586 Words   |  7 PagesRyan Williams English 102 Professor 6 May 2015 The Criminal Justice System: an Analysis of Income and Racial Inequality In the history of civilized communities, one finds that different structures and practices are relevant and necessary to uphold and maintain order within society—hence, the establishment of the criminal justice system. The criminal justice system, according to the Oxford Dictionaries (2010), is defined as â€Å"the system of law enforcement that is directly involved in apprehendingRead MoreThe New Jim Crow : Mass Incarceration1199 Words   |  5 Pagesperceptions on the American criminal justice system? Michelle Alexander was able to accomplish that by altering some people s entire perception on the American criminal justice system by focusing on our most pressing civil right issues of our time for some of those who did read her book The New Jim Crow: Mass Incarceration In The Age of Colorblindness. Michelle Alexander stated that The most despised in America is not gays, transgenders, nor even illegal immigrants - it is criminals. That was anRead MoreRacial Discrimination And The Criminal Justice System1512 Words   |  7 PagesAlthough saying the criminal justice system is racist is a controversial statement, there is evidence and statistics that prove it to be true. Research and evidence validate the issue of racism to be undeniable. Equality and justice are out of reach with the racism that takes place in our criminal justice syste m and our country. Racial discrimination is prevalent amongst the African American culture in issues regarding drug use, and incarceration which creates unfair inequality for this race. I will

Wednesday, May 6, 2020

The Pax Gene Family Encodes For Highly Conserved Dna...

Introduction The Pax gene family encodes for highly conserved DNA-binding transcription factors that play a vital role in embryonic development. All Pax proteins have a paired-box, DNA-binding domain of 128 amino acids located at the amino-terminal end, and is very highly conserved in Drosophila melanogaster, human, and mouse genes (Mansouri et al. 1996). Each different paralogous Pax gene has a crucial role in D. melanogaster and vertebrate development in terms of morphogenesis, organogenesis, cell differentiation, and oncogenesis (Mansouri et al. 1996). However, in this paper, the importance of Pax6’s discovery, mutations, and signaling pathway will be emphasized. It is worthy to note that Pax6 does not operate in a hierarchical linear signaling pathway but instead, in a massive network with numerous feedback loops. It is impossible to cover all possible feedback loops; therefore, the focus of the signaling pathway will be on the lens placode. The Pax6 gene was originally fo und in D. melanogaster corresponding to the eyeless locus (Mansouri et al. 1996). While Pax6 is most famous for its function eye development, it is also prevalent in the pancreas and nervous system development. Since Pax6 encodes a transcription factor that is involved in so many developmental pathways in the eye, pancreas, and nervous system, there is a wide spectrum of defects (Davis et al. 2008). The most common defect is aniridia (absence of the iris) which occurs due to a nonsense mutation

Tuesday, May 5, 2020

Configuring Firms for International Business Sample for Students

Question: Identify the Core Problem Configuring Firms for International Business. Answer: Introduction This section provides overview of the paper; it identifies the core problem to be discussed in configuring firms for international business. Provides an analysis of all problems identified and other alternatives in addition it discusses about the recommendation. The core problem answers major questions regarding Lundbecks structure in Asia. Analysis of the study shows that most markets are trying to get better positions of the market assets. It also discusses the four measures put in place that drives Lundbecks framework which included speed, specialization, compromise and results. A well established business culture in overall market firms will also be analysed as the key point in configuring international firms. Other alternatives will discuss various divided levelled structure which provides larger business task of subdividing the big sections of business association into semi free get-togethers. The recommendations for this case are to introduce a win-win situation that will help configure the firms. They also have to adjust and adapt in different cultural setting. Framework put in place will be an important administration handle for responding to customers change and demand, arranging focus on CNS, revealing strategies of carrying out business and controlling the whole regard chain from R and D to bargains. Problem Statement: The vice president of Lundbeck Michael Anderson and a driver of a pharmaceutical firm in Denmark presented questions regarding Lundbecks structure in Asia. The major points enquired about were; how to get a position of the market assets, problems associated with culture and business and conflict between Rajar and Jun. Analysis In 2005, the Asian market of pharmaceutical had near to 20 percent in general of the industry which was standing at 97.4 billion dollars. This was a rate improvement of each penny of 6.4 a year that was not supposed to change but persist for an additional important drawn-out period (Ajami, 2010). However, most markets in Asia are not the same. Therefore, most markets are trying to get a better position of the market assets. Example in this case is Japan which is the best Asian market standing at each penny of 55 of the whole market and had an increment of 2.4 percent rate per year. China on the other side had an increased rate of more than a percentage of 20 each year and stands at 17.5 for each penny. South Korea is another greatest Asian market together with India, having 8.3% and 8.1% respectively. Other markets stand a percentage rate of 11.3 in each year. (Wang, 2002) Rajar had a wide association throughout Asia with Lundbeck. He greatly likes to help the country directors of Asia ensure their business grows and out of the good achievement he was rewarded. Rajar was placed around executing the Asian Lundbeck system. His success was determined by how good he could build the Asian region and implement that method. Rajar being a timely communicator he gave clear values to Jun who had clear cravings that could reveal a way for Lundbeck Korea which took after the techniques of Lundbeck. Rajar played a big part in organizations and his presence was very important. He also took part in dealing with social affairs and the Asian country chiefs gathering. With the high opinion of administrator Michael Anderson, the association which attempts to involve his principles should pick Rajar to work for them. Since he thinks of the whole firm and ensures the missions and destinations of the association is fulfilled. In case of any issues coming up he definitely wi ll be the appropriate probability to settle conflicts that might arise in the firm. (Lundbeck, 2010) Four measures have been put in place which drives Lundbecks framework, they include; speed, specialization, blend and results. Under speed, the framework uses its small size as excellent position, the aim was to ensure and keep up short important authority handle that will act fast to an increasing market force. In addition, the reason of using small size is for the market to adapt on how to act to risk and how to keep up business practises that are good. For specialization, Lundbeck aim involves; streamlining its major things, advancing CNS business, improve its procedures and business frameworks. To achieve this he focused on passing its news on, displaying resourceful things and maintaining an engaged cost structure. Lundbeck concentrated more on the CNS pharmaceutical range through specialization unlike its opponents who focused on covering a wider part that put more emphasis on broad variety of human administration things and pharmaceutical items. Under compromise Lundbecks aim is changing into a pharmaceutical firm. For the framework to achieve the change, it tried to continue to create strong abilities throughout the market chain that is from data and control of research to pharmaceutical firm, advancing and bargaining. Finally the results were expected to provide reliability to whole deal to its share hold at this moment. Lundbeck had in mind that minimal size firm offers good position for about 70 percent that puts it in a position to set up many assistants. This will eventually settle the conflict arising from different societies due to different business cultures and the aim of Lundbeck is to modify his own way of providing to others. (Bardy, Massaro, Zanin, 2014) Alternatives Various divided levelled structure provides larger business task of subdividing the big sections of business association into semi free get-togethers. The semi free business sections are independently focused on a fixed part of the associations organization. The divided structures also include a couple of parallel gatherings that focuses on a single organisation line. Division of sections are favourable because it allows gathering to focus mainly on one thing or organization with specialists structure which sponsors its main targets. By having pioneer of its own, the division most likely would get all the benefits it wants from the association. For instance in this case, Lundbeck view Asia as a nearby division containing of ten helpers that joined China each having a comparative brand image. However, the different procedures of cooperating their image to be recognized by the whole society , area, district and the public differentiated them which results to improvement in self-governi ng specifically fitted in every area. The advantage of having these divisions is that it provides support, control, course and bearing of reinforcements in the region by Lundbeck. It has the ability of providing control over its allocation, displaying and bargains. At the end it will allow Lundbeck to join Asian market in to its system of speed, specialization, blend and results. The traditional structure is the preferred legitimate structure that suits Lundbeck Korea because it keeps up its image and targets. If Andersen separates Lundbeck Asia from Lundbeck Korea the results will be both negative and positive. On the positive side of the result is that, the separation would allow more development in the market, a mindful social complexity that improves openness amongst neighbourhood. As an outcome of the good conditions, culture of trust will be created. On the other side, the separation would lead to negative outcome which is discussed as the disadvantages brought about by the separation which would result to an ideal condition whereby advertisement and exhibition will be hindered and the movement from the divisions nearby will be disconnected. Also by Andersen separating Lundbeck Asia from Lundbeck Asia there would be alot of burden that could make Lundbeck Korea remain as the major market center and above Lundbeck Asia. The identities of clashing adminis tration could also disconnect the parent division and the backup. In conclusion, if Lundbeck Asia separates from Lundbeck Korea, it possibly would lose support from South Korea and note worthy strong interconnection. (Andersen, 2005) Recommendations: A win-win circumstance is considered to address Anderson issues and will not make Rajar or Jun to leave the organisation. The recommendation on this case would be that the win-win situation should ensure both Jun and Rajar stay in an organization. This will help provide Jun with more opportunities and at the same time Rajar being around he will help regulate operations because of the previous experience he has that makes him well experienced in Asia business. In addition to this the aim is to fulfill the need of each part and therefore keeping them together will be a great idea. As much as their might be strictness relating with each other, they have to identify the idea they share and the criteria they use in approaching circumstances. They also have to adjust and adapt in different cultural setting. Speed as a framework when put in place will be an important administration handle for responding to customers change and demand Reference Ajami, R. (2010). Asia-Pacific Business Practices and Realignments.Journal of Asia-Pacific Business,11(2), 75-77. https://dx.doi.org/10.1080/10599231.2010.481184. Andersen, M. (2005). Special Issue of the International Business Review The changing Chinese culture and business behavior.International Business Review,14(6), 795-796. https://dx.doi.org/10.1016/j.ibusrev.2005.08.003. Bardy, R., Massaro, M., Zanin, F. (2014). Levers of control and knowledge sharing in alliances among Large Firms and Small Firms in the pharmaceutical industry. Management Control , (2), 121-142. https://dx.doi.org/10.3280/maco2014-002006. Lundbeck. (2016, December 24). Lundbeck worldwide. Retrieved March 1, 2017, from https://lundbeck.com/us/about-us/lundbeck-worldwide Lundbeck expands the agreement with Teva to include marketing of Azilect in selected Asian countries (OMX: LUN). (2010, February 24). Retrieved March 1, 2017, from https://investor.lundbeck.com/releasedetail.cfm?releaseid=608603. Wang, N. (2002). China and the Global Business Revolution (review).China Review International,9(2), 507-514. https://dx.doi.org/10.1353/cri.2003.0121.